| NCAAF | 11/15 20:00 | 1 | Wingate Bulldogs v Mars Hill Lions | L | 37-22 | |
| NCAAF | 11/08 18:00 | 1 | Mars Hill Lions v Virginia Wise Highland Cavaliers | W | 60-19 | |
| NCAAF | 11/01 18:00 | 1 | Tusculum Pioneers v Mars Hill Lions | W | 7-28 | |
| NCAAF | 10/25 17:00 | 1 | Mars Hill Lions v Lenoir Rhyne Bears | L | 0-45 | |
| NCAAF | 10/18 22:00 | 1 | Newberry Wolves v Mars Hill Lions | L | 38-24 | |
| NCAAF | 10/11 18:30 | 1 | Mars Hill Lions v Emory And Henry Wasps | L | 23-48 | |
| NCAAF | 10/04 22:00 | 1 | Catawba College v Mars Hill Lions | L | 42-28 | |
| NCAAF | 09/27 17:00 | 1 | Mars Hill Lions v Mary Hardin Baylor | W | 21-7 | |
| NCAAF | 09/20 17:00 | 1 | Mars Hill Lions v Anderson Trojans | W | 21-14 | |
| NCAAF | 09/13 17:00 | 1 | Mars Hill Lions v Carson–Newman Eagles | W | 31-24 | |
| NCAAF | 09/06 22:30 | 1 | Mars Hill Lions v Winston-Salem State | L | 25-28 | |
| NCAAF | 11/16 17:00 | 1 | Limestone Saints v Mars Hill Lions | L | 31-26 | |
| NCAAF | 11/09 21:00 | 1 | Anderson Trojans v Mars Hill Lions | W | 16-31 | |
| NCAAF | 11/02 17:00 | 1 | Mars Hill Lions v Emory And Henry Wasps | W | 31-23 | |
| NCAAF | 10/26 18:00 | 1 | Virginia Wise Highland Cavaliers v Mars Hill Lions | W | 17-31 | |
| NCAAF | 10/19 18:30 | 1 | Mars Hill Lions v Tusculum Pioneers | W | 30-3 | |
| NCAAF | 10/12 17:00 | 1 | Mars Hill Lions v Carson–Newman Eagles | L | 27-28 | |
| NCAAF | 10/05 17:00 | 1 | Newberry Wolves v Mars Hill Lions | W | 9-34 | |
| NCAAF | 09/28 22:00 | 1 | Wingate Bulldogs v Mars Hill Lions | - | Cancelled | |
| NCAAF | 09/21 17:00 | - | Mars Hill Lions v Lenoir Rhyne Bears | L | 21-29 | |
| NCAAF | 08/29 23:00 | - | Mars Hill Lions v Delta State | L | 16-47 | |
| NCAAF | 11/11 18:00 | 1 | Mars Hill Lions v Newberry Wolves | W | 21-14 | |
| NCAAF | 11/04 17:00 | 1 | Tusculum Pioneers v Mars Hill Lions | L | 29-27 | |
| NCAAF | 10/28 17:00 | 1 | Mars Hill Lions v Virginia Wise Highland Cavaliers | W | 49-18 | |
| NCAAF | 10/21 17:00 | 1 | Carson–Newman Eagles v Mars Hill Lions | W | 17-21 | |
| NCAAF | 10/14 17:00 | 1 | Emory And Henry Wasps v Mars Hill Lions | W | 14-24 | |
| NCAAF | 10/07 18:30 | 1 | Mars Hill Lions v Erskine Flying Fleet | W | 38-3 | |
| NCAAF | 09/30 16:00 | 1 | Limestone Saints v Mars Hill Lions | L | 27-23 | |
| NCAAF | 09/23 17:00 | 1 | Mars Hill Lions v Barton Bulldogs | W | 16-14 | |
| NCAAF | 09/16 22:00 | 1 | Catawba College v Mars Hill Lions | W | 20-35 |