| Uruguay Reserve League | 2025/02/24 23:00 | Boston River Reserves v Defensor Sporting Reserves | L | 1-0 |
| Uruguay Reserve League | 2024/12/06 12:00 | Liverpool Montevideo Reserves v Defensor Sporting Reserves | L | 3-2 |
| Uruguay Reserve League | 2024/12/02 20:00 | Defensor Sporting Reserves v Nacional de Montevideo Reserves | D | 0-0 |
| Uruguay Reserve League | 2024/11/28 12:00 | Albion FC Reserves v Defensor Sporting Reserves | W | 0-1 |
| Uruguay Reserve League | 2024/11/18 12:00 | Defensor Sporting Reserves v Atletico River Plate Reserves | W | 5-1 |
| Uruguay Reserve League | 2024/11/11 19:00 | Penarol Reserves v Defensor Sporting Reserves | L | 1-0 |
| Uruguay Reserve League | 2024/11/05 12:00 | Defensor Sporting Reserves v Montevideo Wanderers Reserves | D | 0-0 |
| Uruguay Reserve League | 2024/10/29 12:00 | Danubio Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2025/02/24 19:30 | Juventud De Las Piedras Reserves v Club Oriental Reserves | L | 2-0 |