Stadium: HTC Center
Home Manager: DeLisha Milton-Jones Away Manager: Kevin Pederson
| NIT Women | 2022/03/20 18:00 | Columbia (W) v Old Dominion (W) | L | 62-59 |
| NIT Women | 2022/03/18 23:00 | Old Dominion (W) v Towson Women | W | 72-66 |
| WNCAAB | 2022/03/10 17:30 | North Texas (W) v Old Dominion (W) | L | 65-58 |
| WNCAAB | 2022/03/09 17:30 | Old Dominion (W) v Texas San Antonio (W) | W | 65-45 |
| WNCAAB | 2022/03/05 20:00 | Old Dominion (W) v Middle Tenn St Women | L | 44-62 |
| WNCAAB | 2022/03/02 23:30 | Louisiana Tech Women v Old Dominion (W) | L | 65-62 |
| WNCAAB | 2022/02/26 17:00 | Old Dominion (W) v Florida Intl Women | W | 81-69 |
| WNCAAB | 2022/02/24 23:00 | Old Dominion (W) v Florida Atlantic (W) | W | 70-55 |
| WNCAAB | 2022/03/04 17:30 | Coastal Carolina (W) v Troy (W) | L | 77-99 |
| WNCAAB | 2022/03/02 17:30 | Arkansas State (W) v Coastal Carolina (W) | W | 76-91 |
| WNCAAB | 2022/02/26 19:00 | Troy (W) v Coastal Carolina (W) | L | 71-58 |
| WNCAAB | 2022/02/24 23:00 | South Alabama Women v Coastal Carolina (W) | W | 62-79 |
| WNCAAB | 2022/02/19 18:00 | UT Arlington Women v Coastal Carolina (W) | L | 70-61 |
| WNCAAB | 2022/02/12 19:00 | Coastal Carolina (W) v Georgia Southern (W) | L | 75-90 |
| WNCAAB | 2022/02/10 23:00 | Coastal Carolina (W) v Georgia State (W) | W | 69-62 |
| WNCAAB | 2022/02/05 20:00 | Coastal Carolina (W) v Texas State Women | L | 59-64 |