Stadium: Sanford Coyote Sports Center
Home Manager: Ruth Sinn Away Manager: Kayla Karius
| WNCAAB | 2022/02/18 01:00 | South Dakota (W) v St. Thomas (MN) (W) | L | 73-46 |
| WNCAAB | 2022/01/22 19:00 | St. Thomas (MN) (W) v South Dakota (W) | L | 43-70 |
| WNCAAB | 2022/02/26 18:00 | St. Thomas (MN) (W) v Nebraska Omaha Women | W | 61-56 |
| WNCAAB | 2022/02/25 02:00 | St. Thomas (MN) (W) v Denver Women | L | 63-66 |
| WNCAAB | 2022/02/19 19:00 | South Dakota State (W) v St. Thomas (MN) (W) | L | 83-42 |
| WNCAAB | 2022/02/18 01:00 | South Dakota (W) v St. Thomas (MN) (W) | L | 73-46 |
| WNCAAB | 2022/02/14 19:00 | St. Thomas (MN) (W) v UMKC Women | L | 53-69 |
| WNCAAB | 2022/02/12 19:00 | St. Thomas (MN) (W) v North Dakota State (W) | L | 60-69 |
| WNCAAB | 2022/02/11 01:00 | St. Thomas (MN) (W) v North Dakota Women | L | 61-74 |
| WNCAAB | 2022/02/05 19:00 | Oral Roberts (W) v St. Thomas (MN) (W) | L | 73-67 |
| WNCAAB | 2022/03/26 22:30 | South Dakota (W) v Michigan (W) | L | 49-52 |
| WNCAAB | 2022/03/20 22:00 | South Dakota (W) v Baylor (W) | W | 61-47 |
| WNCAAB | 2022/03/18 17:30 | South Dakota (W) v Mississippi (W) | W | 75-61 |
| WNCAAB | 2022/03/08 19:00 | South Dakota (W) v South Dakota State (W) | W | 56-45 |
| WNCAAB | 2022/03/07 21:00 | South Dakota (W) v UMKC Women | W | 81-67 |
| WNCAAB | 2022/03/05 21:00 | Western Illinois Women v South Dakota (W) | W | 49-75 |
| WNCAAB | 2022/03/01 00:00 | South Dakota (W) v Western Illinois Women | W | 75-48 |
| WNCAAB | 2022/02/26 19:00 | Oral Roberts (W) v South Dakota (W) | W | 49-78 |