Stadium: Thomas F. Ryan Center
Home Manager: Allison Guth Away Manager: Tammi Reiss
| WNCAAB | 2022/03/11 20:30 | Loyola Chicago (W) v Illinois State Women | L | 52-68 |
| WNCAAB | 2022/03/05 19:00 | Missouri State Women v Loyola Chicago (W) | W | 42-60 |
| WNCAAB | 2022/03/04 00:00 | Southern Illinois (W) v Loyola Chicago (W) | L | 51-28 |
| WNCAAB | 2022/02/26 00:00 | Loyola Chicago (W) v Valparaiso Women | W | 66-52 |
| WNCAAB | 2022/02/20 19:00 | Loyola Chicago (W) v Evansville (W) | W | 60-56 |
| WNCAAB | 2022/02/18 23:00 | Loyola Chicago (W) v Indiana State Women | W | 61-59 |
| WNCAAB | 2022/02/15 23:00 | Indiana State Women v Loyola Chicago (W) | W | 40-64 |
| WNCAAB | 2022/02/12 19:00 | Bradley Women v Loyola Chicago (W) | W | 41-56 |
| NIT Women | 2022/03/18 22:00 | Quinnipiac (W) v Rhode Island (W) | L | 61-50 |
| WNCAAB | 2022/03/04 22:00 | St Joseph's Women v Rhode Island (W) | L | 51-48 |
| WNCAAB | 2022/02/26 19:00 | Rhode Island (W) v Dayton Women | L | 46-60 |
| WNCAAB | 2022/02/23 23:00 | St Bonaventure Women v Rhode Island (W) | W | 54-67 |
| WNCAAB | 2022/02/19 21:00 | Rhode Island (W) v Richmond (W) | W | 69-66 |
| WNCAAB | 2022/02/16 23:00 | Dayton Women v Rhode Island (W) | L | 47-37 |
| WNCAAB | 2022/02/13 18:00 | Fordham (W) v Rhode Island (W) | W | 43-58 |
| WNCAAB | 2022/02/10 00:00 | Rhode Island (W) v St Joseph's Women | W | 58-48 |