Stadium: Hulman Center
Home Manager: Kelly Bond-White Away Manager: Chad Killinger
| WNCAAB | 2022/03/11 18:00 | Indiana State (W) v Southern Illinois (W) | W | 61-77 |
| WNCAAB | 2022/02/25 00:00 | Indiana State (W) v Southern Illinois (W) | W | 46-63 |
| WNCAAB | 2022/02/09 23:00 | Southern Illinois (W) v Indiana State (W) | W | 79-55 |
| WNCAAB | 2021/03/11 22:30 | Indiana State (W) v Southern Illinois (W) | W | 89-90 |
| WNCAAB | 2021/02/20 21:00 | Indiana State (W) v Southern Illinois (W) | W | 52-76 |
| WNCAAB | 2021/02/19 23:00 | Southern Illinois (W) v Indiana State (W) | W | 84-69 |
| WNCAAB | 2020/02/22 00:00 | Southern Illinois (W) v Indiana State (W) | W | 60-42 |
| WNCAAB | 2020/01/26 19:00 | Indiana State (W) v Southern Illinois (W) | W | 55-78 |
| WNCAAB | 2022/11/13 01:00 | Middle Tennessee (W) v Southern Illinois (W) | L | 89-38 |
| NIT Women | 2022/03/16 23:00 | Southern Illinois (W) v Purdue (W) | L | 60-82 |
| WNCAAB | 2022/03/12 19:30 | Illinois State Women v Southern Illinois (W) | L | 50-42 |
| WNCAAB | 2022/03/11 18:00 | Indiana State (W) v Southern Illinois (W) | W | 61-77 |
| WNCAAB | 2022/03/05 19:00 | Southern Illinois (W) v Valparaiso Women | L | 54-67 |
| WNCAAB | 2022/03/04 00:00 | Southern Illinois (W) v Loyola Chicago (W) | W | 51-28 |
| WNCAAB | 2022/02/26 20:00 | Evansville (W) v Southern Illinois (W) | W | 66-80 |
| WNCAAB | 2022/02/25 00:00 | Indiana State (W) v Southern Illinois (W) | W | 46-63 |
| WNCAAB | 2022/11/07 16:00 | St Louis Women v Indiana State (W) | W | 62-64 |
| WNCAAB | 2022/03/11 18:00 | Indiana State (W) v Southern Illinois (W) | L | 61-77 |
| WNCAAB | 2022/03/10 22:00 | Indiana State (W) v Evansville (W) | W | 89-75 |
| WNCAAB | 2022/03/05 18:00 | Drake (W) v Indiana State (W) | L | 86-71 |
| WNCAAB | 2022/03/03 23:00 | Northern Iowa (W) v Indiana State (W) | L | 61-55 |
| WNCAAB | 2022/02/26 20:00 | Indiana State (W) v Missouri State Women | L | 65-72 |
| WNCAAB | 2022/02/25 00:00 | Indiana State (W) v Southern Illinois (W) | L | 46-63 |
| WNCAAB | 2022/02/20 18:00 | Valparaiso Women v Indiana State (W) | L | 74-69 |