Stadium: G.B. Hodge Center
Home Manager: Cliff Ellis Away Manager: Dave Dickerson
| NCAAB | 2022/04/01 22:00 | Fresno St v Coastal Carolina | L | 85-74 |
| NCAAB | 2022/03/29 00:00 | Coastal Carolina v South Alabama | W | 69-68 |
| NCAAB | 2022/03/21 23:00 | Florida Gulf Coast v Coastal Carolina | W | 68-84 |
| NCAAB | 2022/03/16 23:00 | Maryland Eastern-Shore v Coastal Carolina | W | 42-66 |
| NCAAB | 2022/03/04 01:30 | Georgia Southern v Coastal Carolina | L | 70-64 |
| NCAAB | 2022/02/26 00:30 | Coastal Carolina v Arkansas LR | W | 68-55 |
| NCAAB | 2022/02/24 01:00 | Coastal Carolina v Arkansas State | W | 74-69 |
| NCAAB | 2022/02/19 21:00 | Troy v Coastal Carolina | W | 63-73 |
| NCAAB | 2022/03/22 00:00 | USC Upstate v South Alabama | L | 79-83 |
| NCAAB | 2022/03/15 22:30 | USC Upstate v Appalachian State | W | 80-74 |
| NCAAB | 2022/03/05 17:00 | USC Upstate v Longwood | L | 70-79 |
| NCAAB | 2022/03/04 19:30 | Charleston Southern v USC Upstate | W | 62-72 |
| NCAAB | 2022/02/26 21:00 | Gardner Webb v USC Upstate | W | 70-72 |
| NCAAB | 2022/02/25 00:00 | USC Upstate v Winthrop | L | 59-89 |
| NCAAB | 2022/02/19 22:30 | USC Upstate v Charleston Southern | W | 78-73 |
| NCAAB | 2022/02/16 23:00 | Presbyterian v USC Upstate | W | 55-60 |