[2] Syracuse 9-19 Pittsburgh [12] 2022-10-03 11:30
Stadium: Acrisure Stadium Round: 1
Home Manager: Dino Babers Away Manager: Pat Narduzzi
Head to Head
| NCAAF | 2021/11/28 00:30 | Pittsburgh v Syracuse | L | 31-14 |
| NCAAF | 2020/09/19 16:00 | Syracuse v Pittsburgh | L | 10-21 |
| NCAAF | 2019/10/18 23:00 | Pittsburgh v Syracuse | L | 27-20 |
| NCAAF | 2018/10/06 16:20 | Syracuse v Pittsburgh | L | 37-44 |
| NCAAF | 2017/10/07 16:30 | Pittsburgh v Syracuse | W | 24-27 |
| NCAAF | 2016/11/26 17:30 | Syracuse v Pittsburgh | L | 61-76 |
| NCAAF | 2015/10/24 16:00 | Syracuse v Pittsburgh | L | 20-23 |
| NCAAF | 2014/11/22 20:30 | Pittsburgh v Syracuse | L | 30-7 |
Home History
| NCAAF | 2022/10/01 21:00 | Wagner v Syracuse | W | 0-59 |
| NCAAF | 2022/09/23 23:00 | Virginia v Syracuse | W | 20-22 |
| NCAAF | 2022/09/17 16:00 | Purdue v Syracuse | W | 29-32 |
| NCAAF | 2022/09/10 23:00 | Syracuse v Connecticut | W | 48-14 |
| NCAAF | 2022/09/04 00:00 | Louisville v Syracuse | W | 7-31 |
| NCAAF | 2021/11/28 00:30 | Pittsburgh v Syracuse | L | 31-14 |
| NCAAF | 2021/11/20 21:00 | Syracuse v NC State | L | 17-41 |
| NCAAF | 2021/11/13 17:00 | Syracuse v Louisville | L | 3-41 |
Away History
| NCAAF | 2022/10/02 00:00 | Georgia Tech v Pittsburgh | L | 26-21 |
| NCAAF | 2022/09/24 16:00 | Rhode Island v Pittsburgh | W | 24-45 |
| NCAAF | 2022/09/17 23:30 | Pittsburgh v Western Michigan | W | 34-13 |
| NCAAF | 2022/09/10 19:30 | Tennessee v Pittsburgh | L | 34-27 |
| NCAAF | 2022/09/01 23:00 | West Virginia v Pittsburgh | W | 31-38 |
| NCAAF Bowl Games | 2021/12/31 00:00 | Pittsburgh v Michigan State | L | 21-31 |
| NCAAF | 2021/12/05 01:00 | Wake Forest v Pittsburgh | W | 21-45 |
| NCAAF | 2021/11/28 00:30 | Pittsburgh v Syracuse | W | 31-14 |