Head to Head
| MLB | 2021/08/12 17:10 | OAK Athletics v CLE Guardians | L | 17-0 |
| MLB | 2021/08/11 23:10 | OAK Athletics v CLE Guardians | L | 6-3 |
| MLB | 2021/08/10 23:10 | OAK Athletics v CLE Guardians | L | 4-3 |
| MLB | 2021/07/18 20:07 | CLE Guardians v OAK Athletics | W | 4-2 |
| MLB | 2021/07/17 20:07 | CLE Guardians v OAK Athletics | W | 3-2 |
| MLB | 2021/07/17 01:40 | CLE Guardians v OAK Athletics | L | 4-5 |
| MLB Exhibition | 2021/03/15 20:05 | OAK Athletics v CLE Guardians | W | 3-7 |
| MLB Spring Training | 2021/03/07 20:05 | CLE Guardians v OAK Athletics | L | 4-9 |
Home History
| MLB | 2021/10/03 19:05 | CLE Guardians v TEX Rangers | W | 6-0 |
| MLB | 2021/10/02 23:05 | CLE Guardians v TEX Rangers | L | 2-7 |
| MLB | 2021/10/02 00:05 | CLE Guardians v TEX Rangers | W | 9-6 |
| MLB | 2021/10/01 00:10 | CLE Guardians v KC Royals | W | 6-1 |
| MLB | 2021/09/30 00:10 | CLE Guardians v KC Royals | L | 5-10 |
| MLB | 2021/09/29 00:10 | CLE Guardians v KC Royals | L | 4-6 |
| MLB | 2021/09/27 17:10 | KC Royals v CLE Guardians | W | 3-8 |
| MLB | 2021/09/26 17:10 | CHI White Sox v CLE Guardians | L | 5-2 |
Away History
| MLB | 2021/10/03 19:10 | OAK Athletics v HOU Astros | L | 6-7 |
| MLB | 2021/10/02 23:10 | OAK Athletics v HOU Astros | L | 4-10 |
| MLB | 2021/10/02 00:10 | OAK Athletics v HOU Astros | W | 8-6 |
| MLB | 2021/09/30 02:10 | OAK Athletics v SEA Mariners | L | 2-4 |
| MLB | 2021/09/29 02:10 | OAK Athletics v SEA Mariners | L | 2-4 |
| MLB | 2021/09/28 02:10 | OAK Athletics v SEA Mariners | L | 4-13 |
| MLB | 2021/09/26 20:07 | HOU Astros v OAK Athletics | W | 3-4 |
| MLB | 2021/09/25 20:07 | HOU Astros v OAK Athletics | W | 1-2 |