Stadium: Fredrick C. Hobdy Assembly Center
Home Manager: Sean Woods Away Manager: Donte' Jackson
| NCAAB | 2021/03/12 02:30 | Southern v Grambling State | L | 67-72 |
| NCAAB | 2021/02/07 01:00 | Grambling State v Southern | L | 72-69 |
| NCAAB | 2021/01/09 23:30 | Southern v Grambling State | W | 61-55 |
| NCAAB | 2020/02/08 23:30 | Southern v Grambling State | L | 62-66 |
| NCAAB | 2020/01/11 23:30 | Grambling State v Southern | L | 61-56 |
| NCAAB | 2019/02/09 23:30 | Grambling State v Southern | L | 59-40 |
| NCAAB | 2019/01/12 23:00 | Southern v Grambling State | L | 63-69 |
| NCAAB | 2018/02/03 23:30 | Grambling State v Southern | L | 69-68 |
| NCAAB | 2021/11/20 01:00 | Southern v South Dakota | L | 68-71 |
| NCAAB | 2021/11/17 01:00 | Southern v Rice | L | 63-81 |
| NCAAB | 2021/11/13 17:30 | Southern v Tulane | W | 73-70 |
| NCAAB | 2021/11/10 03:00 | Southern v Louisville | L | 60-72 |
| NCAAB | 2021/03/12 02:30 | Southern v Grambling State | L | 67-72 |
| NCAAB | 2021/03/06 21:00 | Southern v Texas Southern | L | 74-80 |
| NCAAB | 2021/03/05 01:30 | Southern v Prairie View | L | 61-68 |
| NCAAB | 2021/02/27 22:30 | Alcorn State v Southern | W | 75-89 |
| NCAAB | 2021/11/16 02:00 | Grambling State v New Mexico | L | 61-86 |
| NCAAB | 2021/11/13 01:00 | Grambling State v Texas Tech | L | 62-88 |
| NCAAB | 2021/11/10 02:00 | Grambling State v Grand Canyon | L | 53-74 |
| NCAAB | 2021/03/13 02:30 | Grambling State v Prairie View | L | 63-74 |
| NCAAB | 2021/03/12 02:30 | Southern v Grambling State | W | 67-72 |
| NCAAB | 2021/03/07 02:00 | Alabama A&M v Grambling State | W | 72-80 |
| NCAAB | 2021/03/05 01:30 | Alabama State v Grambling State | W | 68-91 |
| NCAAB | 2021/03/02 01:30 | Grambling State v Mississippi Valley State | L | 63-67 |