Head to Head
| Bolivia Apertura | 2021/05/01 23:30 | Guabira v Real Santa Cruz | L | 1-0 |
| Bolivia Apertura | 2020/12/29 19:00 | Real Santa Cruz v Guabira | D | 4-4 |
| Bolivia Apertura | 2020/03/15 21:15 | Guabira v Real Santa Cruz | L | 1-0 |
Home History
| Bolivia Apertura | 2021/07/26 19:00 | Real Santa Cruz v San Jose | W | 5-0 |
| Bolivia Apertura | 2021/07/20 23:30 | Real Tomayapo v Real Santa Cruz | L | 2-1 |
| Bolivia Apertura | 2021/07/17 19:00 | Real Santa Cruz v Club Aurora | D | 1-1 |
| Bolivia Apertura | 2021/07/11 23:30 | Bolivar v Real Santa Cruz | D | 1-1 |
| Bolivia Apertura | 2021/05/12 19:00 | Real Santa Cruz v Real Potosi | W | 4-1 |
| Bolivia Apertura | 2021/05/07 19:00 | Real Santa Cruz v Blooming | W | 1-0 |
| Bolivia Apertura | 2021/05/01 23:30 | Guabira v Real Santa Cruz | L | 1-0 |
| Bolivia Apertura | 2021/04/09 19:00 | Royal Pari FC v Real Santa Cruz | L | 3-2 |
Away History
| Bolivia Apertura | 2021/07/25 17:00 | Atletico Palmaflor Vinto v Guabira | L | 2-1 |
| Bolivia Apertura | 2021/07/22 19:00 | Guabira v Jorge Wilstermann | W | 3-2 |
| Bolivia Apertura | 2021/07/18 19:00 | The Strongest v Guabira | L | 2-1 |
| Bolivia Apertura | 2021/07/11 21:15 | Guabira v Oriente Petrolero | D | 1-1 |
| Copa Sudamericana | 2021/05/26 22:15 | CA Independiente v Guabira | L | 1-0 |
| Copa Sudamericana | 2021/05/21 00:30 | Guabira v Torque | L | 0-4 |
| Copa Sudamericana | 2021/05/13 22:15 | Guabira v EC Bahia | L | 0-1 |
| Bolivia Apertura | 2021/05/09 19:00 | Nacional Potosi v Guabira | L | 2-1 |