Stadium: Dwight Salzman Stadium Round: 1
| NCAAF | 2019/11/02 17:30 | Manchester Spartans v Bluffton Beavers | W | 14-26 |
| NCAAF | 2018/10/13 17:30 | Bluffton Beavers v Manchester Spartans | L | 17-21 |
| NCAAF | 2021/10/30 17:30 | Rose Hulman Engineers v Bluffton Beavers | L | 48-12 |
| NCAAF | 2021/10/23 17:30 | Bluffton Beavers v Hanover | L | 10-41 |
| NCAAF | 2021/10/16 17:30 | Franklin College Grizzlies v Bluffton Beavers | L | 45-6 |
| NCAAF | 2021/10/09 17:30 | Anderson Ravens v Bluffton Beavers | W | 20-32 |
| NCAAF | 2021/10/02 17:30 | Bluffton Beavers v Mount St. Joseph Lions | L | 27-45 |
| NCAAF | 2021/09/18 17:00 | Kalamazoo Hornets v Bluffton Beavers | W | 20-21 |
| NCAAF | 2021/09/11 17:30 | Bluffton Beavers v St Vincent Bearcats | L | 14-34 |
| NCAAF | 2021/09/04 17:00 | Alma College Scots v Bluffton Beavers | L | 23-0 |
| NCAAF | 2021/10/30 17:30 | Hanover v Manchester Spartans | L | 33-0 |
| NCAAF | 2021/10/23 17:30 | Manchester Spartans v Rose Hulman Engineers | L | 14-57 |
| NCAAF | 2021/10/16 17:30 | Mount St. Joseph Lions v Manchester Spartans | L | 28-0 |
| NCAAF | 2021/10/09 17:30 | Manchester Spartans v Defiance Yellow Jackets | W | 22-0 |
| NCAAF | 2021/10/02 17:30 | Franklin College Grizzlies v Manchester Spartans | W | 24-27 |
| NCAAF | 2021/09/18 17:00 | Olivet Comets v Manchester Spartans | L | 59-7 |
| NCAAF | 2021/09/11 22:00 | Manchester Spartans v Alma College Scots | L | 23-47 |
| NCAAF | 2021/09/02 23:00 | Manchester Spartans v Trine Thunder | L | 14-52 |