[16] ACR Messina 2-1 Monopoli [6] 2021-10-13 11:30
Stadium: San Filippo Round: 22
Referee: Matteo Gualtieri Home Manager: Ezio Raciti Away Manager: Alberto Colombo
Head to Head
| Italy Serie C Group C | 2021/09/12 18:30 | Monopoli v ACR Messina | L | 2-1 |
| Italy Serie C Group C | 2017/03/05 13:30 | ACR Messina v Monopoli | W | 1-0 |
| Italy Serie C Group C | 2016/10/16 14:30 | Monopoli v ACR Messina | L | 2-1 |
| Italy Serie C Group C | 2016/01/30 13:00 | ACR Messina v Monopoli | W | 3-2 |
| Italy Serie C Group C | 2015/09/20 13:00 | Monopoli v ACR Messina | D | 1-1 |
Home History
| Italy Serie C Group C | 2021/10/09 15:00 | ACR Messina v FC Guidonia Montecelio 1937 | L | 1-3 |
| Italy Serie C Group C | 2021/10/03 15:30 | Foggia v ACR Messina | L | 3-1 |
| Italy Serie C Group C | 2021/09/29 15:30 | ACR Messina v Bari | L | 0-2 |
| Italy Serie C Group C | 2021/09/26 12:30 | AZ Picerno ASD v ACR Messina | L | 2-1 |
| Italy Serie D Cup | 2021/09/22 13:00 | ACR Messina v ASD San Luca | W | 4-3 |
| Italy Serie C Group C | 2021/09/19 12:30 | ACR Messina v Virtus Francavilla | W | 1-0 |
| Italy Serie C Cup | 2021/09/15 15:30 | Foggia v ACR Messina | L | 2-0 |
| Italy Serie C Group C | 2021/09/12 18:30 | Monopoli v ACR Messina | L | 2-1 |
Away History
| Italy Serie C Group C | 2021/10/10 15:30 | Monopoli v Campobasso | L | 1-2 |
| Italy Serie C Group C | 2021/10/03 15:30 | Bari v Monopoli | L | 1-0 |
| Italy Serie C Group C | 2021/09/29 16:00 | Monopoli v AZ Picerno ASD | W | 2-0 |
| Italy Serie C Group C | 2021/09/26 12:30 | Virtus Francavilla v Monopoli | L | 3-1 |
| Italy Serie C Group C | 2021/09/20 19:00 | Monopoli v Avellino | D | 0-0 |
| Italy Serie C Cup | 2021/09/15 13:00 | Palermo v Monopoli | L | 2-1 |
| Italy Serie C Group C | 2021/09/12 18:30 | Monopoli v ACR Messina | W | 2-1 |
| Italy Serie C Group C | 2021/09/05 15:30 | SS Turris Calcio v Monopoli | W | 1-2 |