[10] Leyton Orient 3-0 Exeter [15] 2021-03-18 20:00
Stadium: Matchroom Stadium Round: 2
Referee: Tom Reeves Home Manager: Kenneth Francis Jackett Away Manager: Matthew Taylor
Head to Head
| England League 2 | 2021/03/06 13:00 | Exeter v Leyton Orient | L | 4-0 |
| England League 2 | 2020/10/27 19:00 | Leyton Orient v Exeter | D | 1-1 |
| England League 2 | 2019/09/14 14:00 | Exeter v Leyton Orient | D | 2-2 |
| England League 2 | 2017/01/02 15:00 | Exeter v Leyton Orient | L | 4-0 |
| England League 2 | 2016/11/22 19:45 | Leyton Orient v Exeter | L | 0-1 |
| England League 2 | 2016/01/16 15:00 | Leyton Orient v Exeter | L | 1-3 |
| England League 2 | 2015/09/05 14:00 | Exeter v Leyton Orient | L | 4-0 |
Home History
| England League 2 | 2021/03/13 13:00 | Leyton Orient v Scunthorpe | D | 1-1 |
| England League 2 | 2021/03/09 19:00 | Leyton Orient v Stevenage | D | 0-0 |
| England League 2 | 2021/03/06 13:00 | Exeter v Leyton Orient | L | 4-0 |
| England League 2 | 2021/03/02 19:00 | Grimsby v Leyton Orient | W | 0-1 |
| England League 2 | 2021/02/27 15:00 | Leyton Orient v Tranmere | L | 1-3 |
| England League 2 | 2021/02/23 19:00 | Bradford v Leyton Orient | L | 1-0 |
| England League 2 | 2021/02/20 15:00 | Leyton Orient v Port Vale | D | 1-1 |
| England League 2 | 2021/02/06 15:00 | Leyton Orient v Colchester | D | 0-0 |
Away History
| England League 2 | 2021/03/13 15:00 | Exeter v Cheltenham | L | 0-1 |
| England League 2 | 2021/03/09 19:00 | Scunthorpe v Exeter | W | 0-2 |
| England League 2 | 2021/03/06 13:00 | Exeter v Leyton Orient | W | 4-0 |
| England League 2 | 2021/03/02 19:00 | Exeter v Walsall | D | 0-0 |
| England League 2 | 2021/02/27 13:00 | Crawley Town v Exeter | L | 2-0 |
| England League 2 | 2021/02/23 19:00 | Colchester v Exeter | W | 1-2 |
| England League 2 | 2021/02/16 19:00 | Newport County v Exeter | D | 1-1 |
| England League 2 | 2021/02/06 13:00 | Exeter v Bradford | W | 3-2 |