[47] Reilly Opelka 4-6,4-6 Rafael Nadal [3] 2021-01-08 11:50
Stadium: Center Court Round: 28 Ground: Clay
Home History
| ATP Antwerp | 2020/10/21 12:00 | Taylor Fritz v Reilly Opelka | 7-6,6-1 |
| ATP St Petersburg | 2020/10/16 13:20 | Reilly Opelka v Borna Coric | 6-7,3-6 |
| ATP St Petersburg | 2020/10/15 14:00 | Daniil Medvedev v Reilly Opelka | 6-2,5-7,4-6 |
| ATP St Petersburg | 2020/10/14 10:00 | Nino Serdarusic v Reilly Opelka | 6-3,6-7,2-6 |
| French Open | 2020/09/28 10:55 | Reilly Opelka v Jack Sock | 4-6,4-6,3-6 |
| US Open | 2020/08/31 22:35 | Reilly Opelka v David Goffin | 6-7,6-3,1-6,4-6 |
| ATP New York | 2020/08/25 19:55 | Matteo Berrettini v Reilly Opelka | 3-6,6-7 |
| ATP New York | 2020/08/24 17:50 | Reilly Opelka v Diego Schwartzman | 6-3,7-6 |
Away History
| ATP World Tour Finals | 2020/11/21 20:05 | Daniil Medvedev v Rafael Nadal | 3-6,7-6,6-3 |
| ATP World Tour Finals | 2020/11/19 20:25 | Rafael Nadal v Stefanos Tsitsipas | 6-4,4-6,6-2 |
| ATP World Tour Finals | 2020/11/17 14:00 | Rafael Nadal v Dominic Thiem | 6-7,6-7 |
| ATP World Tour Finals | 2020/11/15 20:05 | Rafael Nadal v Andrey Rublev | 6-3,6-4 |
| ATP Paris | 2020/11/07 15:30 | Rafael Nadal v Alexander Zverev | 4-6,5-7 |
| ATP Paris | 2020/11/06 17:30 | Rafael Nadal v Pablo Carreno Busta | 4-6,7-5,6-1 |
| ATP Paris | 2020/11/05 16:20 | Rafael Nadal v Jordan Thompson | 6-1,7-6 |
| ATP Paris | 2020/11/04 17:30 | Rafael Nadal v Feliciano Lopez | 4-6,7-6,6-4 |