Stadium: The Buc Dome Round: 1
Home Manager: Dave Dickerson Away Manager: Barclay Radebaugh
| NCAAB | 2019/03/06 00:00 | USC Upstate v Charleston Southern | L | 52-71 |
| NCAAB | 2019/02/22 00:30 | USC Upstate v Charleston Southern | L | 60-92 |
| NCAAB | 2019/02/02 21:30 | Charleston Southern v USC Upstate | L | 90-71 |
| NCAAB | 2017/11/18 19:00 | USC Upstate v Charleston Southern | L | 72-82 |
| NCAAB | 2016/11/19 22:30 | Charleston Southern v USC Upstate | W | 77-79 |
| NCAAB | 2019/11/23 19:00 | Youngstown State v USC Upstate | L | 66-61 |
| NCAAB | 2019/11/21 00:00 | USC Upstate v Louisville | L | 50-76 |
| NCAAB | 2019/11/19 00:00 | USC Upstate v Akron | L | 45-76 |
| NCAAB | 2019/11/14 00:00 | USC Upstate v Virginia Tech | L | 57-80 |
| NCAAB | 2019/11/12 00:00 | USC Upstate v North Carolina Central | L | 64-73 |
| NCAAB | 2019/11/08 23:00 | USC Upstate v Truett McConnell | W | 103-62 |
| NCAAB | 2019/11/06 00:00 | USC Upstate v Coll of Charleston | L | 55-74 |
| NCAAB | 2019/03/06 00:00 | USC Upstate v Charleston Southern | L | 52-71 |
| NCAAB | 2019/11/24 16:30 | Delaware State v Charleston Southern | W | 61-71 |
| NCAAB | 2019/11/23 16:30 | Southern Utah v Charleston Southern | L | 80-45 |
| NCAAB | 2019/11/18 23:30 | Charleston Southern v Michigan State | L | 46-94 |
| NCAAB | 2019/11/17 00:00 | Charleston Southern v Dayton | L | 61-90 |
| NCAAB | 2019/11/13 00:30 | Furman v Charleston Southern | L | 91-47 |
| NCAAB | 2019/11/09 00:00 | Charleston Southern v North Carolina A&T | L | 49-63 |
| NCAAB | 2019/11/06 00:30 | Charleston Southern v Columbia Intl | W | 99-71 |
| CIT | 2019/03/26 23:00 | Charleston Southern v Hampton | L | 67-73 |