Stadium: Mangelsdorf Field Round: 1
| NCAAF | 2022/11/12 18:00 | Misericordia Cougars v Lycoming Warriors | W | 21-14 |
| NCAAF | 2022/11/05 16:00 | Kings Monarchs v Misericordia Cougars | L | 14-0 |
| NCAAF | 2022/10/29 16:00 | Misericordia Cougars v Stevenson Mustangs | L | 7-44 |
| NCAAF | 2022/10/15 16:00 | Wilkes Colonels v Misericordia Cougars | L | 28-0 |
| NCAAF | 2022/10/08 17:00 | Misericordia Cougars v Lebanon Valley Flying Dutchmen | L | 12-47 |
| NCAAF | 2022/10/01 17:00 | Misericordia Cougars v Fdu Florham Devils | L | 14-28 |
| NCAAF | 2022/09/24 17:00 | Delaware Valley Aggies v Misericordia Cougars | L | 41-0 |
| NCAAF | 2022/09/17 16:00 | Albright Lions v Misericordia Cougars | W | 21-27 |