Stadium: James H. Hilton Coliseum
| WNCAAB | 2021/11/21 18:00 | Southern (W) v Iowa State (W) | L | 55-96 |
| WNCAAB | 2019/11/08 00:30 | Iowa State (W) v Southern (W) | L | 69-36 |
| WNCAAB | 2022/03/11 23:30 | Jackson State (W) v Southern (W) | L | 59-46 |
| WNCAAB | 2022/03/10 23:30 | Southern (W) v Texas Southern Women | W | 68-67 |
| WNCAAB | 2022/03/05 20:00 | Southern (W) v Alabama A&M (W) | L | 67-73 |
| WNCAAB | 2022/03/03 23:30 | Southern (W) v Alabama State Women | L | 46-64 |
| WNCAAB | 2022/02/28 23:30 | Florida A&M Women v Southern (W) | W | 43-66 |
| WNCAAB | 2022/02/26 21:00 | Bethune Cookman (W) v Southern (W) | W | 51-65 |
| WNCAAB | 2022/02/19 20:00 | Grambling State (W) v Southern (W) | W | 49-59 |
| WNCAAB | 2022/02/14 23:30 | Southern (W) v Texas Southern Women | L | 77-87 |
| WNCAAB | 2022/03/26 01:30 | Creighton (W) v Iowa State (W) | L | 76-68 |
| WNCAAB | 2022/03/21 00:00 | Georgia Women v Iowa State (W) | W | 44-67 |
| WNCAAB | 2022/03/19 02:00 | UT Arlington Women v Iowa State (W) | W | 71-78 |
| WNCAAB | 2022/03/12 20:30 | Iowa State (W) v Texas (W) | L | 73-82 |
| WNCAAB | 2022/03/11 23:00 | West Virginia (W) v Iowa State (W) | W | 60-66 |
| WNCAAB | 2022/03/06 00:00 | Iowa State (W) v West Virginia (W) | W | 74-57 |
| WNCAAB | 2022/03/01 00:00 | Baylor (W) v Iowa State (W) | L | 87-62 |
| WNCAAB | 2022/02/26 19:00 | Texas Tech Women v Iowa State (W) | W | 55-71 |