Stadium: G.B. Hodge Center
Home Manager: Dave Dickerson Away Manager: Tony Stockman
| NCAAB | 2022/03/22 00:00 | USC Upstate v South Alabama | L | 79-83 |
| NCAAB | 2022/03/15 22:30 | USC Upstate v Appalachian State | W | 80-74 |
| NCAAB | 2022/03/05 17:00 | USC Upstate v Longwood | L | 70-79 |
| NCAAB | 2022/03/04 19:30 | Charleston Southern v USC Upstate | W | 62-72 |
| NCAAB | 2022/02/26 21:00 | Gardner Webb v USC Upstate | W | 70-72 |
| NCAAB | 2022/02/25 00:00 | USC Upstate v Winthrop | L | 59-89 |
| NCAAB | 2022/02/19 22:30 | USC Upstate v Charleston Southern | W | 78-73 |
| NCAAB | 2022/02/16 23:00 | Presbyterian v USC Upstate | W | 55-60 |
| NCAAB | 2021/12/08 00:00 | Campbell v Columbia Intl | L | 74-56 |
| NCAAB | 2021/11/25 00:00 | Gardner Webb v Columbia Intl | L | 90-78 |
| NCAAB | 2020/12/18 21:00 | Appalachian State v Columbia Intl | L | 77-41 |
| NCAAB | 2020/12/18 00:00 | East Tenn St v Columbia Intl | L | 96-54 |
| NCAAB | 2020/12/12 18:00 | Liberty v Columbia Intl | L | 73-26 |
| NCAAB | 2020/12/08 00:00 | The Citadel v Columbia Intl | L | 96-57 |
| NCAAB | 2020/12/05 15:00 | Mercer v Columbia Intl | L | 88-62 |
| NCAAB | 2020/12/03 23:00 | Coastal Carolina v Columbia Intl | L | 113-56 |