Stadium: Ford Center Round: 3
Home Manager: Rechelle Turner Away Manager: Samantha Quigley Smith
| WNCAAB | 2021/02/20 22:30 | Murray State (W) v SIU Edwardsville (W) | W | 68-60 |
| WNCAAB | 2021/01/09 19:00 | SIU Edwardsville (W) v Murray State (W) | L | 64-57 |
| WNCAAB | 2020/02/22 22:30 | SIU Edwardsville (W) v Murray State (W) | W | 61-70 |
| WNCAAB | 2020/02/01 23:00 | Murray State (W) v SIU Edwardsville (W) | W | 74-60 |
| WNCAAB | 2019/02/09 23:00 | Murray State (W) v SIU Edwardsville (W) | W | 81-75 |
| WNCAAB | 2019/01/19 20:00 | Murray State (W) v SIU Edwardsville (W) | L | 54-71 |
| WNCAAB | 2018/02/11 00:00 | SIU Edwardsville (W) v Murray State (W) | L | 77-68 |
| WNCAAB | 2017/12/30 23:00 | Murray State (W) v SIU Edwardsville (W) | L | 70-75 |
| WNCAAB | 2021/12/04 20:00 | Murray State (W) v Samford (W) | L | 66-75 |
| WNCAAB | 2021/12/01 00:00 | Murray State (W) v Evansville (W) | W | 85-77 |
| WNCAAB | 2021/11/27 19:00 | Alabama A&M (W) v Murray State (W) | W | 40-66 |
| WNCAAB | 2021/11/23 17:00 | Murray State (W) v Mississippi Valley State (W) | W | 74-50 |
| WNCAAB | 2021/11/20 00:00 | Murray State (W) v Chattanooga Women | W | 78-55 |
| WNCAAB | 2021/11/16 00:00 | Murray State (W) v Cumberlands (KY) Women | W | 94-56 |
| WNCAAB | 2021/11/12 01:00 | Murray State (W) v Missouri (W) | L | 70-76 |
| WNCAAB | 2021/11/09 17:00 | Murray State (W) v Asbury Women | W | 79-40 |
| WNCAAB | 2021/12/11 19:00 | Illinois State Women v SIU Edwardsville (W) | L | 80-71 |
| WNCAAB | 2021/12/10 01:00 | St Louis Women v SIU Edwardsville (W) | W | 57-63 |
| WNCAAB | 2021/12/08 00:00 | Western Illinois Women v SIU Edwardsville (W) | L | 96-93 |
| WNCAAB | 2021/12/03 01:00 | SIU Edwardsville (W) v Missouri (W) | L | 46-79 |
| WNCAAB | 2021/11/28 20:00 | Purdue Fort Wayne Women v SIU Edwardsville (W) | W | 56-68 |
| WNCAAB | 2021/11/23 17:00 | SIU Edwardsville (W) v Butler (W) | W | 87-74 |
| WNCAAB | 2021/11/19 01:00 | SIU Edwardsville (W) v Illinois (W) | W | 71-62 |
| WNCAAB | 2021/11/14 20:00 | SIU Edwardsville (W) v Memphis Women | L | 58-89 |