Stadium: Hertz Arena
Home Manager: Tory Verdi Away Manager: Bill Fennelly
| WNCAAB | 2021/03/22 20:00 | Ohio (W) v Massachusetts (W) | W | 71-95 |
| WNCAAB | 2021/03/20 18:00 | Charlotte Women v Massachusetts (W) | W | 75-81 |
| WNCAAB | 2021/03/20 00:00 | Massachusetts (W) v Villanova Women | L | 51-78 |
| WNCAAB | 2021/03/14 16:00 | Massachusetts (W) v VA Commonwealth Women | L | 69-81 |
| WNCAAB | 2021/03/13 21:00 | Massachusetts (W) v St Louis Women | W | 90-81 |
| WNCAAB | 2021/03/12 22:00 | Massachusetts (W) v Fordham (W) | W | 80-70 |
| WNCAAB | 2021/03/11 22:00 | St Joseph's Women v Massachusetts (W) | W | 69-79 |
| WNCAAB | 2021/02/28 21:30 | Massachusetts (W) v Richmond (W) | W | 70-65 |
| WNCAAB | 2021/03/24 23:00 | Iowa State (W) v Texas A&M (W) | L | 82-84 |
| WNCAAB | 2021/03/22 22:00 | Michigan State (W) v Iowa State (W) | W | 75-79 |
| WNCAAB | 2021/03/12 16:30 | Texas (W) v Iowa State (W) | L | 84-82 |
| WNCAAB | 2021/03/04 00:30 | Kansas Women v Iowa State (W) | W | 53-83 |
| WNCAAB | 2021/02/25 00:30 | West Virginia (W) v Iowa State (W) | W | 68-85 |
| WNCAAB | 2021/02/20 19:00 | Iowa State (W) v Oklahoma State (W) | L | 73-80 |
| WNCAAB | 2021/02/18 01:00 | Kansas Women v Iowa State (W) | W | 82-84 |
| WNCAAB | 2021/02/14 01:00 | TCU (W) v Iowa State (W) | W | 81-92 |