Stadium: Murphy Center
Home Manager: Kim McNeill Away Manager: Rick Insell
| WNCAAB | 2021/03/10 03:00 | East Carolina (W) v Houston (W) | L | 63-73 |
| WNCAAB | 2021/03/03 00:00 | East Carolina (W) v Tulane (W) | L | 60-77 |
| WNCAAB | 2021/02/27 18:00 | Memphis (W) v East Carolina (W) | W | 62-81 |
| WNCAAB | 2021/02/24 23:00 | East Carolina (W) v Cincinnati (W) | L | 61-76 |
| WNCAAB | 2021/02/20 18:00 | East Carolina (W) v Wichita State Women | W | 74-59 |
| WNCAAB | 2021/02/13 17:00 | Temple (W) v East Carolina (W) | L | 58-57 |
| WNCAAB | 2021/02/06 23:00 | Memphis (W) v East Carolina (W) | W | 53-67 |
| WNCAAB | 2021/01/30 20:30 | East Carolina (W) v Tulsa (W) | L | 59-68 |
| WNCAAB | 2021/03/21 18:00 | Middle Tennessee (W) v Tennessee (W) | L | 62-87 |
| WNCAAB | 2021/03/13 23:00 | Middle Tennessee (W) v Rice (W) | W | 68-65 |
| WNCAAB | 2021/03/13 02:30 | UTEP (W) v Middle Tennessee (W) | W | 58-74 |
| WNCAAB | 2021/03/11 20:00 | Louisiana Tech (W) v Middle Tennessee (W) | W | 71-77 |
| WNCAAB | 2021/03/06 00:00 | Marshall (W) v Middle Tennessee (W) | W | 54-61 |
| WNCAAB | 2021/03/05 00:00 | Marshall (W) v Middle Tennessee (W) | L | 72-49 |
| WNCAAB | 2021/02/27 22:00 | Middle Tennessee (W) v Old Dominion (W) | W | 74-70 |
| WNCAAB | 2021/02/27 00:00 | Old Dominion (W) v Middle Tennessee (W) | L | 74-57 |