[2] BUF Sabres 1-2 NJ Devils [12] 2021-10-08 13:00
Stadium: Prudential Center
Home Manager: Don Granato Away Manager: Lindy Ruff
Head to Head
| NHL | 2021/04/08 23:00 | NJ Devils v BUF Sabres | L | 6-3 |
| NHL | 2021/04/06 23:00 | BUF Sabres v NJ Devils | W | 5-3 |
| NHL | 2021/03/16 23:00 | BUF Sabres v NJ Devils | L | 2-3 |
| NHL | 2021/02/26 00:00 | NJ Devils v BUF Sabres | L | 4-3 |
| NHL | 2021/02/24 00:00 | BUF Sabres v NJ Devils | W | 4-1 |
| NHL | 2021/02/20 17:30 | BUF Sabres v NJ Devils | W | 3-2 |
| NHL | 2021/01/31 18:00 | NJ Devils v BUF Sabres | L | 5-3 |
| NHL | 2021/01/30 18:00 | NJ Devils v BUF Sabres | W | 3-4 |
Home History
| NHL Pre-Season | 2021/10/05 23:00 | BUF Sabres v PIT Penguins | L | 4-5 |
| NHL Pre-Season | 2021/10/04 23:00 | CLB Blue Jackets v BUF Sabres | L | 5-3 |
| NHL Pre-Season | 2021/10/01 23:00 | PIT Penguins v BUF Sabres | L | 2-1 |
| NHL Pre-Season | 2021/09/30 23:30 | BUF Sabres v DET Red Wings | L | 2-6 |
| NHL Pre-Season | 2021/09/28 23:00 | BUF Sabres v CLB Blue Jackets | W | 5-4 |
| NHL | 2021/05/08 19:00 | BUF Sabres v PIT Penguins | L | 0-1 |
| NHL | 2021/05/06 23:00 | BUF Sabres v PIT Penguins | L | 4-8 |
| NHL | 2021/05/04 23:00 | NY Islanders v BUF Sabres | W | 3-4 |
Away History
| NHL Pre-Season | 2021/10/06 23:00 | NJ Devils v NY Rangers | L | 2-6 |
| NHL Pre-Season | 2021/10/04 23:00 | WAS Capitals v NJ Devils | W | 1-4 |
| NHL Pre-Season | 2021/10/02 18:00 | NJ Devils v NY Islanders | W | 2-1 |
| NHL Pre-Season | 2021/10/01 23:00 | NY Rangers v NJ Devils | W | 1-7 |
| NHL Pre-Season | 2021/09/29 23:00 | NJ Devils v WAS Capitals | W | 5-4 |
| NHL | 2021/05/10 23:00 | NJ Devils v PHI Flyers | L | 2-4 |
| NHL | 2021/05/08 23:00 | NJ Devils v NY Islanders | L | 1-5 |
| NHL | 2021/05/06 23:00 | NJ Devils v NY Islanders | W | 2-1 |