[60] Lorenzo Musetti 6-7,5-7,4-6 Reilly Opelka [24] 2021-07-12 04:00
Stadium: Stadium 17 Round: 24 Ground: Hardcourt outdoor
Home History
| Wimbledon | 2021/06/29 16:50 | Hubert Hurkacz v Lorenzo Musetti | 6-4,7-6,6-1 |
| French Open | 2021/06/05 09:00 | Marco Cecchinato v Lorenzo Musetti | 6-3,4-6,3-6,6-3,3-6 |
| French Open | 2021/06/03 10:55 | Yoshihito Nishioka v Lorenzo Musetti | 5-7,3-6,2-6 |
| French Open | 2021/05/31 16:15 | Lorenzo Musetti v David Goffin | 6-0,7-5,7-6 |
| ATP Parma | 2021/05/26 15:10 | Lorenzo Musetti v Yoshihito Nishioka | 3-6,2-6 |
| ATP Parma | 2021/05/25 11:30 | Gianluca Mager v Lorenzo Musetti | 6-4,1-6,2-6 |
| ATP Lyon | 2021/05/22 12:00 | Lorenzo Musetti v Stefanos Tsitsipas | 6-4,3-6,0-6 |
| ATP Lyon | 2021/05/21 08:30 | Lorenzo Musetti v Aljaz Bedene | 6-3,7-6 |
Away History
| Wimbledon | 2021/06/28 16:15 | Reilly Opelka v Dominik Koepfer | 4-6,6-7,2-6 |
| ATP Queens | 2021/06/14 11:30 | Reilly Opelka v John Millman | 6-7,7-5,6-7 |
| French Open | 2021/06/04 13:40 | Reilly Opelka v Daniil Medvedev | 4-6,2-6,4-6 |
| French Open | 2021/06/02 13:45 | Reilly Opelka v Jaume Munar | 6-3,6-2,3-6,7-5 |
| French Open | 2021/05/31 12:15 | Reilly Opelka v Andrej Martin | 6-3,6-2,6-4 |
| ATP Geneva | 2021/05/18 11:10 | Pablo Cuevas v Reilly Opelka | 7-6,6-2 |
| ATP Rome | 2021/05/15 13:50 | Reilly Opelka v Rafael Nadal | 4-6,4-6 |
| ATP Rome | 2021/05/14 08:00 | Federico Delbonis v Reilly Opelka | 5-7,6-7 |