[81] Indiana State 15-10 Illinois State [78] 2021-09-10 02:00
Stadium: Hancock Stadium Round: 1
Home Manager: Curt Mallory Away Manager: Brock Spack
Head to Head
| NCAAF | 2019/10/26 19:00 | Indiana State v Illinois State | L | 7-24 |
| NCAAF FCS | 2018/11/10 18:00 | Illinois State v Indiana State | W | 23-28 |
| NCAAF | 2017/09/30 23:30 | Illinois State v Indiana State | L | 24-13 |
Home History
| NCAAF | 2021/08/28 22:00 | Eastern Illinois v Indiana State | W | 21-26 |
| NCAAF | 2019/11/23 20:00 | Indiana State v Missouri St | W | 51-24 |
| NCAAF | 2019/11/16 18:00 | Youngstown State v Indiana State | W | 17-24 |
| NCAAF | 2019/11/09 22:00 | Indiana State v Northern Iowa | L | 9-17 |
| NCAAF | 2019/11/02 17:00 | SO Illinois v Indiana State | L | 23-14 |
| NCAAF | 2019/10/26 19:00 | Indiana State v Illinois State | L | 7-24 |
| NCAAF | 2019/10/19 17:00 | South Dakota State v Indiana State | L | 42-23 |
| NCAAF | 2019/10/12 17:00 | Western Illinois v Indiana State | W | 10-20 |
Away History
| NCAAF | 2021/09/04 23:30 | Butler v Illinois State | W | 7-49 |
| NCAAF | 2021/03/20 16:00 | Western Illinois v Illinois State | W | 18-26 |
| NCAAF | 2021/03/13 20:30 | Illinois State v North Dakota State | L | 13-21 |
| NCAAF | 2021/03/06 22:00 | Illinois State v Northern Iowa | L | 10-20 |
| NCAAF | 2021/02/27 18:00 | South Dakota v Illinois State | L | 27-20 |
| NCAAF | 2019/12/14 17:00 | Illinois State v North Dakota State | L | 3-9 |
| NCAAF | 2019/12/07 20:00 | Illinois State v Central Arkansas | W | 24-14 |
| NCAAF | 2019/11/30 19:00 | Illinois State v SE Missouri St | W | 24-6 |