Stadium: Estadio Rogelio Silvino Livieres Round: 14
Referee: Carlos P. Benitez Home Manager: Gustavo Costas Away Manager: Gustavo Florentin
| Paraguay Division Profesional | 2021/02/27 22:30 | Sol de America v Guarani Asuncion | W | 1-3 |
| Paraguay Division Profesional | 2020/10/17 21:00 | Sol de America v Guarani Asuncion | L | 1-0 |
| Paraguay Division Profesional | 2020/09/12 21:30 | Sol de America v Guarani Asuncion | W | 1-2 |
| Paraguay Division Profesional | 2020/03/07 23:45 | Guarani Asuncion v Sol de America | D | 1-1 |
| Paraguay Division Profesional | 2019/12/01 21:00 | Guarani Asuncion v Sol de America | L | 0-1 |
| Paraguay Division Profesional | 2019/09/14 22:30 | Sol de America v Guarani Asuncion | W | 0-1 |
| Paraguay Division Profesional | 2019/05/11 21:00 | Guarani Asuncion v Sol de America | W | 3-1 |
| Paraguay Division Profesional | 2019/03/10 23:45 | Sol de America v Guarani Asuncion | W | 1-4 |
| Paraguay Division Profesional | 2021/04/02 00:30 | Nacional Asuncion v Guarani Asuncion | L | 2-0 |
| Paraguay Division Profesional | 2021/03/28 23:00 | Libertad Asuncion v Guarani Asuncion | D | 1-1 |
| Paraguay Division Profesional | 2021/03/21 21:15 | Cerro Porteno v Guarani Asuncion | L | 2-1 |
| Copa Libertadores Qualification | 2021/03/19 00:30 | Atletico Nacional Medellin v Guarani Asuncion | L | 3-0 |
| Paraguay Division Profesional | 2021/03/14 20:45 | Guarani Asuncion v Guairena FC | L | 0-3 |
| Copa Libertadores Qualification | 2021/03/12 00:30 | Guarani Asuncion v Atletico Nacional Medellin | L | 0-2 |
| Paraguay Division Profesional | 2021/03/07 22:30 | Guarani Asuncion v Sportivo Luqueno | L | 0-1 |
| Copa Libertadores Qualification | 2021/03/04 00:30 | Guarani Asuncion v Royal Pari FC | D | 1-1 |
| Paraguay Division Profesional | 2021/04/04 23:00 | Cerro Porteno v Sol de America | L | 1-0 |
| Paraguay Division Profesional | 2021/03/22 21:15 | Guairena FC v Sol de America | D | 2-2 |
| Paraguay Division Profesional | 2021/03/13 23:45 | Sol de America v Libertad Asuncion | L | 0-2 |
| Paraguay Division Profesional | 2021/03/10 23:45 | Sportivo Luqueno v Sol de America | D | 0-0 |
| Paraguay Division Profesional | 2021/03/06 23:30 | Sol de America v Olimpia Asuncion | L | 0-2 |
| Paraguay Division Profesional | 2021/02/27 22:30 | Sol de America v Guarani Asuncion | L | 1-3 |
| Paraguay Division Profesional | 2021/02/20 21:30 | 12 de Octubre v Sol de America | W | 0-5 |
| Paraguay Division Profesional | 2021/02/15 21:30 | Sol de America v River Plate Asuncion | D | 1-1 |