Stadium: Alamodome Round: 122
Home Manager: Suzy Merchant Away Manager: Bill Fennelly
| WNCAAB | 2021/01/10 20:00 | Michigan State (W) v Nebraska (W) | L | 64-68 |
| WNCAAB | 2021/01/07 22:00 | Maryland (W) v Michigan State (W) | L | 93-87 |
| WNCAAB | 2021/01/03 19:00 | Purdue Women v Michigan State (W) | W | 64-71 |
| WNCAAB | 2020/12/22 17:00 | Oakland (W) v Michigan State (W) | W | 56-94 |
| WNCAAB | 2020/12/20 20:00 | Michigan State (W) v Northern Illinois (W) | W | 82-70 |
| WNCAAB | 2020/12/18 22:00 | Central Michigan Women v Michigan State (W) | W | 70-79 |
| WNCAAB | 2020/12/12 21:00 | Iowa (W) v Michigan State (W) | W | 82-86 |
| WNCAAB | 2020/12/10 02:00 | Michigan State (W) v Minnesota (W) | W | 81-68 |
| WNCAAB | 2021/01/20 00:30 | Oklahoma (W) v Iowa State (W) | W | 63-64 |
| WNCAAB | 2021/01/17 01:00 | Iowa State (W) v Baylor (W) | W | 75-71 |
| WNCAAB | 2021/01/14 00:30 | Oklahoma State (W) v Iowa State (W) | W | 80-90 |
| WNCAAB | 2021/01/10 21:00 | Iowa State (W) v Texas Tech Women | W | 99-72 |
| WNCAAB | 2021/01/03 20:00 | Iowa State (W) v Texas (W) | L | 59-74 |
| WNCAAB | 2020/12/23 00:00 | Drake (W) v Iowa State (W) | W | 67-85 |
| WNCAAB | 2020/12/19 00:00 | Kansas State (W) v Iowa State (W) | W | 69-91 |
| WNCAAB | 2020/12/16 00:30 | Iowa State (W) v Northern Iowa Women | W | 67-61 |