[22] BUF Sabres 4-7 OTT Senators [29] 2019-10-10 18:30
Stadium: Canadian Tire Centre
Home Manager: Away Manager: Ralph Krueger
Head to Head
| NHL | 2019/04/04 23:00 | OTT Senators v BUF Sabres | W | 2-5 |
| NHL | 2019/03/26 23:30 | BUF Sabres v OTT Senators | L | 0-4 |
| NHL | 2018/11/03 18:00 | OTT Senators v BUF Sabres | W | 2-9 |
| NHL | 2018/11/01 23:30 | BUF Sabres v OTT Senators | L | 2-4 |
| NHL | 2018/04/04 23:30 | OTT Senators v BUF Sabres | L | 4-2 |
| NHL | 2018/03/09 00:30 | BUF Sabres v OTT Senators | W | 4-3 |
| NHL | 2018/02/16 00:30 | BUF Sabres v OTT Senators | L | 2-3 |
| NHL | 2017/12/13 00:00 | OTT Senators v BUF Sabres | W | 2-3 |
Home History
| NHL | 2019/10/09 23:00 | MTL Canadiens v BUF Sabres | W | 4-5 |
| NHL | 2019/10/07 23:00 | BUF Sabres v CLB Blue Jackets | L | 3-4 |
| NHL | 2019/10/05 23:00 | NJ Devils v BUF Sabres | W | 2-7 |
| NHL | 2019/10/03 23:00 | BUF Sabres v PIT Penguins | W | 3-1 |
| NHL Pre-Season | 2019/09/28 20:00 | BUF Sabres v PIT Penguins | W | 3-2 |
| NHL Pre-Season | 2019/09/25 23:00 | CLB Blue Jackets v BUF Sabres | W | 3-4 |
| NHL Pre-Season | 2019/09/21 23:00 | TOR Maple Leafs v BUF Sabres | W | 3-5 |
| NHL Pre-Season | 2019/09/20 23:00 | BUF Sabres v TOR Maple Leafs | L | 0-3 |
Away History
| NHL | 2019/10/05 23:00 | NY Rangers v OTT Senators | L | 4-1 |
| NHL | 2019/10/02 23:00 | OTT Senators v TOR Maple Leafs | L | 3-5 |
| NHL Pre-Season | 2019/09/28 23:00 | OTT Senators v MTL Canadiens | L | 3-4 |
| NHL Pre-Season | 2019/09/26 02:00 | OTT Senators v VAN Canucks | W | 6-2 |
| NHL Pre-Season | 2019/09/24 02:00 | OTT Senators v VAN Canucks | L | 4-6 |
| NHL Pre-Season | 2019/09/21 23:30 | MTL Canadiens v OTT Senators | L | 4-0 |
| NHL Pre-Season | 2019/09/18 23:30 | TOR Maple Leafs v OTT Senators | W | 3-4 |
| NHL Pre-Season | 2019/09/17 21:30 | OTT Senators v TOR Maple Leafs | W | 3-1 |