[22] BUF Sabres 1-4 SJ Sharks [7] 2016-10-21 12:30
Stadium: SAP Center at San Jose Round: 1
Home History
| NHL | 2016/10/21 02:00 | BUF Sabres v VAN Canucks | L | 1-2 |
| NHL | 2016/10/19 01:00 | BUF Sabres v CGY Flames | L | 3-4 |
| NHL | 2016/10/16 23:00 | BUF Sabres v EDM Oilers | W | 6-2 |
| NHL | 2016/10/13 23:00 | MTL Canadiens v BUF Sabres | L | 4-1 |
| NHL Pre-Season | 2016/10/04 22:58 | CAR Hurricanes v BUF Sabres | W | 0-2 |
Away History
| NHL | 2016/10/20 23:00 | SJ Sharks v PIT Penguins | L | 2-3 |
| NHL | 2016/10/18 23:00 | SJ Sharks v NY Islanders | W | 3-2 |
| NHL | 2016/10/17 22:45 | SJ Sharks v NY Rangers | L | 4-7 |
| NHL | 2016/10/15 23:00 | SJ Sharks v CLB Blue Jackets | W | 3-2 |
| NHL | 2016/10/13 02:30 | LA Kings v SJ Sharks | W | 1-2 |
| NHL Pre-Season | 2016/10/09 23:59 | SJ Sharks v ANA Ducks | L | 2-3 |
| NHL Pre-Season | 2016/10/02 23:45 | SJ Sharks v VAN Canucks | D | 2-2 |