Stadium: Knapp Center Round: 1
Home Manager: Jennie Baranczyk Away Manager: Cindy Stein
| WNCAAB | 2018/03/10 19:30 | Southern Illinois (W) v Drake (W) | W | 59-68 |
| WNCAAB | 2018/02/03 01:00 | Drake (W) v Southern Illinois (W) | W | 84-73 |
| WNCAAB | 2018/01/07 20:00 | Southern Illinois (W) v Drake (W) | W | 64-75 |
| WNCAAB | 2018/12/22 00:00 | Drake (W) v Iowa (W) | L | 82-91 |
| WNCAAB | 2018/12/16 18:00 | Iowa State (W) v Drake (W) | L | 86-81 |
| WNCAAB | 2018/12/08 20:00 | South Dakota State (W) v Drake (W) | L | 80-71 |
| WNCAAB | 2018/12/04 17:00 | Drake (W) v Clarke Crusaders Women | W | 91-43 |
| WNCAAB | 2018/11/28 18:00 | Creighton (W) v Drake (W) | W | 69-85 |
| WNCAAB | 2018/11/25 03:30 | South Carolina (W) v Drake (W) | W | 85-90 |
| WNCAAB | 2018/11/24 02:00 | Drake (W) v Notre Dame (W) | L | 64-82 |
| WNCAAB | 2018/11/22 22:30 | Drake (W) v Rutgers (W) | W | 69-59 |
| WNCAAB | 2018/12/21 20:00 | Southern Illinois (W) v IU Indianapolis Women | W | 78-73 |
| WNCAAB | 2018/12/18 23:00 | Murray State (W) v Southern Illinois (W) | W | 59-65 |
| WNCAAB | 2018/12/08 21:30 | Southern Illinois (W) v Eastern Illinois (W) | W | 73-59 |
| WNCAAB | 2018/12/08 01:00 | Southern Illinois (W) v Northern Illinois (W) | W | 82-73 |
| WNCAAB | 2018/11/30 01:00 | Saint Louis (W) v Southern Illinois (W) | L | 62-58 |
| WNCAAB | 2018/11/24 22:30 | Arizona State (W) v Southern Illinois (W) | L | 82-38 |
| WNCAAB | 2018/11/23 20:00 | Hartford Women v Southern Illinois (W) | W | 50-72 |
| WNCAAB | 2018/11/20 17:00 | Western Kentucky (W) v Southern Illinois (W) | L | 83-76 |